Is There Any Pure Atorvastatin Tablet Without Salt?

When it comes to pharmaceutical preparations, the presence of various excipients in medications can sometimes lead to questions among patients. In the case of atorvastatin, a common question arises: can one find a pure atorvastatin tablet free of additional salts or excipients?

Atorvastatin is a medication used to lower cholesterol, and it is commonly found in formulations such as Lipitor (atorvastatin calcium). However, many consumers wonder if a pure atorvastatin tablet exists, devoid of any salt or other additives. Let's explore this topic and clarify any doubts.

Understanding Atorvastatin and Its Formulations

Atorvastatin, the active ingredient, is a HMG-CoA reductase inhibitor used to reduce high cholesterol levels. While it is indeed a pure compound, the tablets available on the market include various excipients to enhance their stability, disintegration, and patient compliance.

Excipients and Their Functions

Excipients are non-medicinal substances used in the preparation and manufacturing of medicines. These can include binders, disintegrants, fillers, lubricants, and other substances. One of the common excipients found in atorvastatin tablets is croscarmellose sodium, which is a cross-linked polymer of carboxymethylcellulose sodium. This excipient is used to ensure that the tablet disintegrates properly in the body and does not leave any undissolved particles.

What is Croscarmellose Sodium?

Croscarmellose sodium, also known as sodium CMC, is a white fibrous, free-flowing powder. It is FDA-approved and is widely used in pharmaceutical manufacturing as a disintegrant. Disintegrants help the tablet to break down into small particles, making it easier for the medicine to be released and absorbed by the body.

Scanning the Market for Salt-Free Atorvastatin Tablets

While atorvastatin itself is a pure compound, the search for a salt-free tablet is practically non-existent in the market. The excipients used in the formulation are essential for the overall performance and safety of the medication. However, some patients may have specific needs or preferences and may seek a salt-free version.

CVS Caremark Atorvastatin Solution

CVS Caremark, a leading pharmacy benefit manager, offers a solution for those who are concerned about potential salt content in their medications. CVS Caremark's Atorvastatin Solution is a highly purified form of the drug, designed to be free of any additional salts or other excipients. This solution can be dispensed by a compounding pharmacy and tailored to meet the individual patient's requirements.

Conclusion

In conclusion, while atorvastatin as a pure compound does not contain additional salts, the actual tablets you find on the market include various excipients, such as croscarmellose sodium, for their optimal function. However, for those with specific dietary needs or concerns, compounding pharmacies offer solutions like CVS Caremark's Atorvastatin Solution, which can be customized to meet individual preferences.

Key Takeaways

Atorvastatin as a pure compound does not contain additional salts. Croscarmellose sodium is a common excipient used as a disintegrant. CVS Caremark's Atorvastatin Solution is a salt-free option dispensed by compounding pharmacies.

References

For more information, consult the following resources:

Mayo Clinic FDA CVS Health